High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism

Dietary guidelines for obesity typically focus on three food groups (carbohydrates, fat, and protein) and caloric restriction. Intake of noncaloric nutrients, such as salt, are rarely discussed. However, recently high salt intake has been reported to predict the development of obesity and insulin re...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Lanaspa, Miguel A., Kuwabara, Masanari, Andres-Hernando, Ana, Li, Nanxing, Cicerchi, Christina, Jensen, Thomas, Orlicky, David J., Roncal-Jimenez, Carlos A., Ishimoto, Takuji, Nakagawa, Takahiko, Rodriguez-Iturbe, Bernardo, MacLean, Paul S., Johnson, Richard J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2018
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866545/
https://ncbi.nlm.nih.gov/pubmed/29507217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713837115
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