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Deletion of fructokinase in the liver or in the intestine reveals differential effects on sugar-induced metabolic dysfunction

Intake of fructose-containing sugars is strongly associated with metabolic syndrome. Dietary fructose is uniquely metabolized versus other sugars by fructokinase. However, the tissue-specific role of fructokinase in sugar-induced metabolic syndrome and the specific roles of glucose and fructose in d...

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Publicado en:Cell Metab
Main Authors: Andres-Hernando, Ana, Orlicky, David J., Kuwabara, Masanari, Ishimoto, Takuji, Nakagawa, Takahiko, Johnson, Richard J., Lanaspa, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347444/
https://ncbi.nlm.nih.gov/pubmed/32502381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.05.012
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