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High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism

Dietary guidelines for obesity typically focus on three food groups (carbohydrates, fat, and protein) and caloric restriction. Intake of noncaloric nutrients, such as salt, are rarely discussed. However, recently high salt intake has been reported to predict the development of obesity and insulin re...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lanaspa, Miguel A., Kuwabara, Masanari, Andres-Hernando, Ana, Li, Nanxing, Cicerchi, Christina, Jensen, Thomas, Orlicky, David J., Roncal-Jimenez, Carlos A., Ishimoto, Takuji, Nakagawa, Takahiko, Rodriguez-Iturbe, Bernardo, MacLean, Paul S., Johnson, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866545/
https://ncbi.nlm.nih.gov/pubmed/29507217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713837115
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