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Membrane protein structure in live cells: Methodology for studying drug interaction by mass spectrometry-based footprinting

Mass spectrometry (MS) based footprinting is an emerging approach to study protein structure. Because integral membrane proteins are difficult targets for conventional structural biology, we recently developed a MS footprinting method to probe membrane protein/drug interactions in live cells. This m...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Shen, Guomin, Li, Shuang, Cui, Weidong, Liu, Shixuan, Yang, Yihu, Gross, Michael, Li, Weikai
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862532/
https://ncbi.nlm.nih.gov/pubmed/29192498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00874
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