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Mass spectrometry-based footprinting of protein–protein interactions
We present a high-resolution mass spectrometric (MS) footprinting method enabling identification of contact amino acids in protein–protein complexes. The method is based on comparing surface topologies of a free protein versus its complex with the binding partner using differential accessibility of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673337/ https://ncbi.nlm.nih.gov/pubmed/19015031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2008.10.023 |
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