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Probing Conformational Changes of Human DNA Polymerase λ Using Mass Spectrometry-Based Protein Footprinting

Crystallographic studies of the C-terminal, DNA polymerase β-like domain of human DNA polymerase lambda (fPolλ) suggested that the catalytic cycle might not involve a large protein domain rearrangement as observed with several replicative DNA polymerases and DNA polymerase β. To examine solution-pha...

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Hlavní autoři: Fowler, Jason D., Brown, Jessica A., Kvaratskhelia, Mamuka, Suo, Zucai
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724185/
https://ncbi.nlm.nih.gov/pubmed/19467241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.05.037
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