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Efficiency and Fidelity of Human DNA Polymerases λ and β during Gap-Filling DNA Synthesis

The base excision repair (BER) pathway coordinates the replacement of 1 to 10 nucleotides at sites of single-base lesions. This process generates DNA substrates with various gap sizes which can alter the catalytic efficiency and fidelity of a DNA polymerase during gap-filling DNA synthesis. Here, we...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Brown, Jessica A., Pack, Lindsey R., Sanman, Laura E., Suo, Zucai
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065367/
https://ncbi.nlm.nih.gov/pubmed/20961817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.09.005
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