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Efficiency and Fidelity of Human DNA Polymerases λ and β during Gap-Filling DNA Synthesis
The base excision repair (BER) pathway coordinates the replacement of 1 to 10 nucleotides at sites of single-base lesions. This process generates DNA substrates with various gap sizes which can alter the catalytic efficiency and fidelity of a DNA polymerase during gap-filling DNA synthesis. Here, we...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3065367/ https://ncbi.nlm.nih.gov/pubmed/20961817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.09.005 |
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