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Rare variant association test in family-based sequencing studies

The objective of this article is to introduce valid and robust methods for the analysis of rare variants for family-based exome chips, whole-exome sequencing or whole-genome sequencing data. Family-based designs provide unique opportunities to detect genetic variants that complement studies of unrel...

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Bibliografische gegevens
Gepubliceerd in:Brief Bioinform
Hoofdauteurs: Wang, Xuefeng, Zhang, Zhenyu, Morris, Nathan, Cai, Tianxi, Lee, Seunggeun, Wang, Chaolong, Yu, Timothy W, Walsh, Christopher A, Lin, Xihong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862290/
https://ncbi.nlm.nih.gov/pubmed/27677958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbw083
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