Metabolic Syndrome Induces Over Expression of the Human AT1R: A Haplotype-Dependent Effect With Implications on Cardio-Renal Function

BACKGROUND: The transcriptional regulation of the human angiotensin receptor subtype 1 (AT1R) gene in pathophysiologies, like the metabolic syndrome, is poorly understood. The human AT1R gene has polymorphisms in its promoter that can be arranged in 2 haplotypes. Variants -810T, -713T, -214A, and -1...

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Detalhes bibliográficos
Publicado no:Am J Hypertens
Main Authors: Jain, Sudhir, Puri, Nitin, Rana, Anita, Sirianni, Natalie, Mopidevi, Brahmaraju, Kumar, Ashok
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Original Contributions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861552/
https://ncbi.nlm.nih.gov/pubmed/29036458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpx176
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