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A Haplotype of Angiotensin Receptor Type 1 Associated with Human Hypertension Increases Blood Pressure in Transgenic Mice
The renin-angiotensin system plays an important role in the regulation of blood pressure via angiotensin II and the angiotensin II receptor type 1 (AT(1)R). Human AT(1)R gene promoter has four SNPs: T/A at −777, T/G at −680, A/C at −214, and A/G at −119, that are in linkage disequilibrium. Variants...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3873561/ https://ncbi.nlm.nih.gov/pubmed/24202179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.520023 |
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