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A haplotype of human angiotensinogen gene containing −217A increases blood pressure in transgenic mice compared with −217G
The human angiotensinogen (hAGT) gene contains an A/G polymorphism at −217, and frequency of −217A allele is increased in African-American hypertensive patients. The hAGT gene has seven polymorphic sites in the 1.2-kb region of its promoter, and variant −217A almost always occurs with −532T, −793A,...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Physiological Society
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685293/ https://ncbi.nlm.nih.gov/pubmed/18945948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.90637.2008 |
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