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The transcriptional regulation of the human angiotensinogen gene after high-fat diet is haplotype-dependent: Novel insights into the gene-regulatory networks and implications for human hypertension

Single nucleotide polymorphisms (SNPs) in the human angiotensinogen (hAGT) gene may modulate its transcription and affect the regulation of blood pressure via activation of the renin-angiotensin aldosterone system (RAAS). In this regard, we have identified polymorphisms in the 2.5 Kb promoter of the...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Rana, Anita, Jain, Sudhir, Puri, Nitin, Kaw, Meenakshi, Sirianni, Natalie, Eren, Deniz, Mopidevi, Brahma Raju, Kumar, Ashok
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415177/
https://ncbi.nlm.nih.gov/pubmed/28467442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176373
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