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Structural characterization of the Asf1–Rtt109 interaction and its role in histone acetylation

Acetylation of histone H3 at lysine-56 by the histone acetyltransferase Rtt109 in lower eukaryotes is important for maintaining genomic integrity and is required for C. albicans pathogenicity. Rtt109 is activated by association with two different histone chaperones, Vps75 and Asf1, through an unknow...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Lercher, Lukas, Danilenko, Nataliya, Kirkpatrick, John, Carlomagno, Teresa
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861439/
https://ncbi.nlm.nih.gov/pubmed/29300933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1283
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