Multisite substrate recognition in Asf1-dependent acetylation of histone H3 K56 by Rtt109

Rtt109 is a unique histone acetyltransferase acetylating histone H3 lysine 56 (H3K56), a modification critical for DNA replication-coupled nucleosome assembly and genome stability. In cells, histone chaperone Asf1 is essential for H3K56 acetylation, yet the mechanisms for H3K56 specificity and Asf1...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Zhang, Lin, Serra-Cardona, Albert, Zhou, Hui, Wang, Mingzhu, Yang, Na, Zhang, Zhiguo, Xu, Rui-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103222/
https://ncbi.nlm.nih.gov/pubmed/30057113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.07.005
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