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Yeast Rtt109 promotes genome stability by acetylating histone H3 on lysine 56

Post-translational modificationsof the histone octamer play important roles in regulating responses to DNA damage. Here, we reveal that Saccharomyces cerevisiae Rtt109p promotes genome stability and resistance to DNA damaging agents, and that it does this by functionally cooperating with the histone...

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Autori principali: Driscoll, Robert, Hudson, Amanda, Jackson, Stephen P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334813/
https://ncbi.nlm.nih.gov/pubmed/17272722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1135862
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