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Rtt109 slows replication speed by histone N-terminal acetylation

The wrapping of DNA around histone octamers challenges processes that use DNA as their template. In vitro, DNA replication through chromatin depends on histone modifiers, raising the possibility that cells modify histones to optimize fork progression. Rtt109 is an acetyl transferase that acetylates...

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Detalles Bibliográficos
Publicado en:Genome Res
Main Authors: Frenkel, Nelly, Jonas, Felix, Carmi, Miri, Yaakov, Gilad, Barkai, Naama
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919450/
https://ncbi.nlm.nih.gov/pubmed/33563717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.266510.120
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