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Rtt109 slows replication speed by histone N-terminal acetylation

The wrapping of DNA around histone octamers challenges processes that use DNA as their template. In vitro, DNA replication through chromatin depends on histone modifiers, raising the possibility that cells modify histones to optimize fork progression. Rtt109 is an acetyl transferase that acetylates...

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Bibliografiske detaljer
Udgivet i:Genome Res
Main Authors: Frenkel, Nelly, Jonas, Felix, Carmi, Miri, Yaakov, Gilad, Barkai, Naama
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919450/
https://ncbi.nlm.nih.gov/pubmed/33563717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.266510.120
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