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Rtt109 slows replication speed by histone N-terminal acetylation

The wrapping of DNA around histone octamers challenges processes that use DNA as their template. In vitro, DNA replication through chromatin depends on histone modifiers, raising the possibility that cells modify histones to optimize fork progression. Rtt109 is an acetyl transferase that acetylates...

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Bibliografske podrobnosti
izdano v:Genome Res
Main Authors: Frenkel, Nelly, Jonas, Felix, Carmi, Miri, Yaakov, Gilad, Barkai, Naama
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919450/
https://ncbi.nlm.nih.gov/pubmed/33563717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.266510.120
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