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Histone chaperone exploits intrinsic disorder to switch acetylation specificity

Histones, the principal protein components of chromatin, contain long disordered sequences, which are extensively post-translationally modified. Although histone chaperones are known to control both the activity and specificity of histone-modifying enzymes, the mechanisms promoting modification of h...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Danilenko, Nataliya, Lercher, Lukas, Kirkpatrick, John, Gabel, Frank, Codutti, Luca, Carlomagno, Teresa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684614/
https://ncbi.nlm.nih.gov/pubmed/31387991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11410-7
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