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Histone chaperone exploits intrinsic disorder to switch acetylation specificity
Histones, the principal protein components of chromatin, contain long disordered sequences, which are extensively post-translationally modified. Although histone chaperones are known to control both the activity and specificity of histone-modifying enzymes, the mechanisms promoting modification of h...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6684614/ https://ncbi.nlm.nih.gov/pubmed/31387991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11410-7 |
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