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In silico identification of rescue sites by double force scanning
MOTIVATION: A deleterious amino acid change in a protein can be compensated by a second-site rescue mutation. These compensatory mechanisms can be mimicked by drugs. In particular, the location of rescue mutations can be used to identify protein regions that can be targeted by small molecules to rea...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5860198/ https://ncbi.nlm.nih.gov/pubmed/28961796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx515 |
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