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Detection of allosteric signal transmission by information-theoretic analysis of protein dynamics

Allostery offers a highly specific way to modulate protein function. Therefore, understanding this mechanism is of increasing interest for protein science and drug discovery. However, allosteric signal transmission is difficult to detect experimentally and to model because it is often mediated by lo...

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Detalhes bibliográficos
Main Authors: Pandini, Alessandro, Fornili, Arianna, Fraternali, Franca, Kleinjung, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290435/
https://ncbi.nlm.nih.gov/pubmed/22071506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-190868
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