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In silico identification of rescue sites by double force scanning

MOTIVATION: A deleterious amino acid change in a protein can be compensated by a second-site rescue mutation. These compensatory mechanisms can be mimicked by drugs. In particular, the location of rescue mutations can be used to identify protein regions that can be targeted by small molecules to rea...

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Bibliografski detalji
Izdano u:Bioinformatics
Glavni autori: Tiberti, Matteo, Pandini, Alessandro, Fraternali, Franca, Fornili, Arianna
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860198/
https://ncbi.nlm.nih.gov/pubmed/28961796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx515
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