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In Silico Phosphorylation of the Autoinhibited Form of p47(phox): Insights into the Mechanism of Activation
Activation of the multicomponent enzyme NADPH oxidase requires the interaction between the tandem SH3 domain of the cytosolic subunit p47(phox) and the cytoplasmic tail of membrane-bound p22(phox). In the resting state, p47(phox) exists in an autoinhibited conformation stabilized by intramolecular c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998635/ https://ncbi.nlm.nih.gov/pubmed/21112296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.09.008 |
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