Molecular Insights of p47(phox) Phosphorylation Dynamics in the Regulation of NADPH Oxidase Activation and Superoxide Production

Phagocyte superoxide production by a multicomponent NADPH oxidase is important in host defense against microbial invasion. However inappropriate NADPH oxidase activation causes inflammation. Endothelial cells express NADPH oxidase and endothelial oxidative stress due to prolonged NADPH oxidase activ...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Meijles, Daniel N., Fan, Lampson M., Howlin, Brendan J., Li, Jian-Mei
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Computational Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132782/
https://ncbi.nlm.nih.gov/pubmed/24970888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.561159
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