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Molecular Insights of p47(phox) Phosphorylation Dynamics in the Regulation of NADPH Oxidase Activation and Superoxide Production

Phagocyte superoxide production by a multicomponent NADPH oxidase is important in host defense against microbial invasion. However inappropriate NADPH oxidase activation causes inflammation. Endothelial cells express NADPH oxidase and endothelial oxidative stress due to prolonged NADPH oxidase activ...

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Bibliografiske detaljer
Main Authors: Meijles, Daniel N., Fan, Lampson M., Howlin, Brendan J., Li, Jian-Mei
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132782/
https://ncbi.nlm.nih.gov/pubmed/24970888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.561159
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