Molecular Insights of p47(phox) Phosphorylation Dynamics in the Regulation of NADPH Oxidase Activation and Superoxide Production

Phagocyte superoxide production by a multicomponent NADPH oxidase is important in host defense against microbial invasion. However inappropriate NADPH oxidase activation causes inflammation. Endothelial cells express NADPH oxidase and endothelial oxidative stress due to prolonged NADPH oxidase activ...

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Detalhes bibliográficos
Principais autores: Meijles, Daniel N., Fan, Lampson M., Howlin, Brendan J., Li, Jian-Mei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Computational Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132782/
https://ncbi.nlm.nih.gov/pubmed/24970888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.561159
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