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Altered levels of the splicing factor muscleblind modifies cerebral cortical function in mouse models of myotonic dystrophy
Myotonic dystrophy (DM) is a progressive, multisystem disorder affecting skeletal muscle, heart, and central nervous system. In both DM1 and DM2, microsatellite expansions of CUG and CCUG RNA repeats, respectively, accumulate and disrupt functions of alternative splicing factors, including musclebli...
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| Veröffentlicht in: | Neurobiol Dis |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5859959/ https://ncbi.nlm.nih.gov/pubmed/29331264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.01.003 |
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