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Altered levels of the splicing factor muscleblind modifies cerebral cortical function in mouse models of myotonic dystrophy

Myotonic dystrophy (DM) is a progressive, multisystem disorder affecting skeletal muscle, heart, and central nervous system. In both DM1 and DM2, microsatellite expansions of CUG and CCUG RNA repeats, respectively, accumulate and disrupt functions of alternative splicing factors, including musclebli...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Chen, Gang, Carter, Russell E., Cleary, John D., Reid, Tammy S., Ranum, Laura P., Swanson, Maurice S., Ebner, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859959/
https://ncbi.nlm.nih.gov/pubmed/29331264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.01.003
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