RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2

Several microsatellite-expansion diseases are characterized by the accumulation of RNA foci and RAN proteins raising the possibility of a mechanistic connection. We explored this question using myotonic dystrophy type 2, a multisystemic disease thought to be primarily caused by RNA gain-of-function...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Neuron
Autores principales: Zu, Tao, Cleary, John D., Liu, Yuanjing, Bañez-Coronel, Monica, Bubenik, Jodi L., Ayhan, Fatma, Ashizawa, Tetsuo, Xia, Guangbin, Clark, H. Brent, Yachnis, Anthony T., Swanson, Maurice S., Ranum, Laura P.W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951173/
https://ncbi.nlm.nih.gov/pubmed/28910618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.08.039
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares