A carregar...
Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy
Myotonic dystrophy (DM1) is an autosomal dominant neuromuscular disorder associated with a (CTG)(n) expansion in the 3′-untranslated region of the DM1 protein kinase (DMPK) gene. To explain disease pathogenesis, the RNA dominance model proposes that the DM1 mutation produces a gain-of-function at th...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC302046/ https://ncbi.nlm.nih.gov/pubmed/10970838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.17.4439 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|