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Short Tandem Repeat Expansions and RNA-Mediated Pathogenesis in Myotonic Dystrophy

Short tandem repeat (STR) or microsatellite, expansions underlie more than 50 hereditary neurological, neuromuscular and other diseases, including myotonic dystrophy types 1 (DM1) and 2 (DM2). Current disease models for DM1 and DM2 propose a common pathomechanism, whereby the transcription of mutant...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Sznajder, Łukasz J., Swanson, Maurice S.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651174/
https://ncbi.nlm.nih.gov/pubmed/31323950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20133365
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