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High-Level Production and Properties of the Cysteine-Depleted Cytochrome P450 3A4
Human drug-metabolizing cytochrome P450 3A4 (CYP3A4) is a dynamic enzyme with a large and highly malleable active site that can fit structurally diverse compounds. Despite extensive investigations, structure–function relationships and conformational dynamics in CYP3A4 are not fully understood. This...
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| Gepubliceerd in: | Biochemistry |
|---|---|
| Hoofdauteur: | |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5858725/ https://ncbi.nlm.nih.gov/pubmed/28590129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00334 |
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