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Chronic exposure to tumor necrosis factor alpha induces retinal pigment epithelium cell dedifferentiation
BACKGROUND: The retinal pigment epithelium (RPE) is a monolayer of pigmented cells with important barrier and immuno-suppressive functions in the eye. We have previously shown that acute stimulation of RPE cells by tumor necrosis factor alpha (TNFα) downregulates the expression of OTX2 (Orthodenticl...
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| Veröffentlicht in: | J Neuroinflammation |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5857126/ https://ncbi.nlm.nih.gov/pubmed/29548329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1106-8 |
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