IL-1β induces rod degeneration through the disruption of retinal glutamate homeostasis

BACKGROUND: Age-related macular degeneration is characterized by the accumulation of subretinal macrophages and the degeneration of cones, but mainly of rods. We have previously shown that Mononuclear Phagocytes-derived IL-1β induces rod photoreceptor cell death during experimental subretinal inflam...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Charles-Messance, Hugo, Blot, Guillaume, Couturier, Aude, Vignaud, Lucile, Touhami, Sara, Beguier, Fanny, Siqueiros, Lourdes, Forster, Valérie, Barmo, Nour, Augustin, Sébastien, Picaud, Serge, Sahel, José-Alain, Rendon, Alvaro, Grosche, Antje, Tadayoni, Ramin, Sennlaub, Florian, Guillonneau, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942287/
https://ncbi.nlm.nih.gov/pubmed/31900165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1655-5
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