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Site-Specific Cleavage by Topoisomerase 2: A Mark of the Core Centromere

In addition to its roles in transcription and replication, topoisomerase 2 (topo 2) is crucial in shaping mitotic chromosomes and in ensuring the orderly separation of sister chromatids. As well as its recruitment throughout the length of the mitotic chromosome, topo 2 accumulates at the primary con...

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Pubblicato in:Int J Mol Sci
Autori principali: Mills, Walter E., Spence, Jennifer M., Fukagawa, Tatsuo, Farr, Christine J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855756/
https://ncbi.nlm.nih.gov/pubmed/29439406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020534
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