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Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X α-satellite array

Dissection of human centromeres is difficult because of the lack of landmarks within highly repeated DNA. We have systematically manipulated a single human X centromere generating a large series of deletion derivatives, which have been examined at four levels: linear DNA structure; the distribution...

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Detalhes bibliográficos
Main Authors: Spence, Jennifer M., Critcher, Ricky, Ebersole, Thomas A., Valdivia, Manuel M., Earnshaw, William C., Fukagawa, Tatsuo, Farr, Christine J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129033/
https://ncbi.nlm.nih.gov/pubmed/12356743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf511
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