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Stereocontrolled Synthesis of Kalihinol C

We report a concise chemical synthesis of kalihinol C via a possible biosynthetic intermediate, ‘protokalihinol,’ which was targeted as a scaffold en route to antiplasmodial analogs. High stereocontrol of the kalihinol framework relies on a heterodendralene cascade to establish the target stereotetr...

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Publicado en:J Am Chem Soc
Main Authors: Reiher, Christopher A., Shenvi, Ryan A.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854479/
https://ncbi.nlm.nih.gov/pubmed/28252949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01124
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