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Synthesis and Potent Antimalarial Activity of Kalihinol B

[Image: see text] Of the 50+ kalihinane diterpenoids reported to date, only five had been tested for antimalarial activity, in spite of the fact that kalihinol A is the most potent among the members of the larger family of antimalarial isocyanoterpenes. We have validated a strategy designed to acces...

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Publicat a:J Am Chem Soc
Autors principals: Daub, Mary Elisabeth, Prudhomme, Jacques, Le Roch, Karine, Vanderwal, Christopher D.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2015
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415034/
https://ncbi.nlm.nih.gov/pubmed/25815413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b01152
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