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Imaging of pre-mRNA splicing in living subjects using a genetically encoded luciferase reporter
Pre-mRNA splicing is an essential step in gene expression in most eukaryote genes. Here we present the feasibility of a genetically encoded luciferase reporter to monitor the pre-mRNA splicing process in living cells and animals. We showed that the splicing activity change induced by isoginkgetin co...
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| 出版年: | Biomed Opt Express |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Optical Society of America
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5854055/ https://ncbi.nlm.nih.gov/pubmed/29552390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.9.000518 |
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