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Rational Design of an Activatable Reporter for Quantitative Imaging of RNA Aberrant Splicing In Vivo

Pre-mRNA splicing, the process of removing introns from pre-mRNA and the arrangement of exons to produce mature transcripts, is a crucial step in the expression of most eukaryote genes. However, the splicing kinetics remain poorly characterized in living cells, mainly because current methods cannot...

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書誌詳細
出版年:Mol Ther Methods Clin Dev
主要な著者: Xie, Jinrong, Zheng, Haifeng, Chen, Si, Shi, Xiaorui, Mao, Wenjie, Wang, Fu
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Gene & Cell Therapy 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210378/
https://ncbi.nlm.nih.gov/pubmed/32405512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.04.007
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