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A ratiometric dual luciferase reporter for quantitative monitoring of pre-mRNA splicing efficiency in vivo
Precursor messenger RNA (pre-mRNA) splicing is critical for cell growth and development, and errors in RNA splicing frequently cause cellular dysfunction, abnormal gene expression, and a variety of human diseases. However, there is currently a lack of reliable systems to noninvasively monitor the mR...
Guardado en:
| Publicado en: | J Biol Chem |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8322121/ https://ncbi.nlm.nih.gov/pubmed/34216622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100933 |
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