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Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors
We have examined the functional significance of the organization of pre- mRNA splicing factors in a speckled distribution in the mammalian cell nucleus. Upon microinjection into living cells of oligonucleotides or antibodies that inhibit pre-mRNA splicing in vitro, we observed major changes in the o...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1994
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2119927/ https://ncbi.nlm.nih.gov/pubmed/8294510 |
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