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Structural characterisation of the catalytic domain of botulinum neurotoxin X - high activity and unique substrate specificity

Botulinum neurotoxins (BoNTs) are among the most potent toxins known and are also used to treat an increasing number of medical disorders. There are seven well-established serotypes (BoNT/A-G), which all act as zinc-dependent endopeptidases targeting specific members of the SNARE proteins required f...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Masuyer, Geoffrey, Zhang, Sicai, Barkho, Sulyman, Shen, Yi, Henriksson, Linda, Košenina, Sara, Dong, Min, Stenmark, Pål
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851995/
https://ncbi.nlm.nih.gov/pubmed/29540745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22842-4
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