Structural and Biochemical Characterization of Botulinum Neurotoxin Subtype B2 Binding to Its Receptors

Botulinum neurotoxins (BoNTs) can be used therapeutically to treat a wide range of neuromuscular and neurological conditions. A collection of natural BoNT variants exists which can be classified into serologically distinct serotypes (BoNT/B), and further divided into subtypes (BoNT/B1, B2, …). BoNT...

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Bibliografiska uppgifter
Huvudupphovsmän: Jonathan R. Davies, Geoffrey Masuyer, Pål Stenmark
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI AG 2020-09-01
Serie:Toxins
Ämnen:
<i>Clostridium botulinum</i>
botulism
botulinum neurotoxin
BoNT/B
synaptotagmin
ganglioside
Länkar:https://www.mdpi.com/2072-6651/12/9/603
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