Structural and Biochemical Characterization of Botulinum Neurotoxin Subtype B2 Binding to Its Receptors

Botulinum neurotoxins (BoNTs) can be used therapeutically to treat a wide range of neuromuscular and neurological conditions. A collection of natural BoNT variants exists which can be classified into serologically distinct serotypes (BoNT/B), and further divided into subtypes (BoNT/B1, B2, …). BoNT...

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Bibliographic Details
Main Authors: Jonathan R. Davies, Geoffrey Masuyer, Pål Stenmark
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-09-01
Series:Toxins
Subjects:
<i>Clostridium botulinum</i>
botulism
botulinum neurotoxin
BoNT/B
synaptotagmin
ganglioside
Online Access:https://www.mdpi.com/2072-6651/12/9/603
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