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Crystal Structure of Botulinum Neurotoxin A2 in Complex with the Human Protein Receptor SV2C Reveals Plasticity in Receptor Binding

Botulinum neurotoxins (BoNTs) are a family of highly dangerous bacterial toxins, with seven major serotypes (BoNT/A-G). Members of BoNTs, BoNT/A1 and BoNT/B1, have been utilized to treat an increasing number of medical conditions. The clinical trials are ongoing for BoNT/A2, another subtype of BoNT/...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Toxins (Basel)
Päätekijät: Gustafsson, Robert, Zhang, Sicai, Masuyer, Geoffrey, Dong, Min, Stenmark, Pål
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923319/
https://ncbi.nlm.nih.gov/pubmed/29649119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10040153
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