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Structure of dual receptor binding to botulinum neurotoxin B
Botulinum neurotoxins are highly toxic, and bind two receptors to achieve their high affinity and specificity for neurons. Here we present the first structure of a botulinum neurotoxin bound to both its receptors. We determine the 2.3 Å structure of a ternary complex of botulinum neurotoxin type B b...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752466/ https://ncbi.nlm.nih.gov/pubmed/23807078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3058 |
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