Early structural and functional plasticity alterations in a susceptibility period of DYT1 dystonia mouse striatum

The onset of abnormal movements in DYT1 dystonia is between childhood and adolescence, although it is unclear why clinical manifestations appear during this developmental period. Plasticity at corticostriatal synapses is critically involved in motor memory. In the Tor1a(+/Δgag) DYT1 dystonia mouse m...

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Veröffentlicht in:eLife
Hauptverfasser: Maltese, Marta, Stanic, Jennifer, Tassone, Annalisa, Sciamanna, Giuseppe, Ponterio, Giulia, Vanni, Valentina, Martella, Giuseppina, Imbriani, Paola, Bonsi, Paola, Mercuri, Nicola Biagio, Gardoni, Fabrizio, Pisani, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2018
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849413/
https://ncbi.nlm.nih.gov/pubmed/29504938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33331
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