Early structural and functional plasticity alterations in a susceptibility period of DYT1 dystonia mouse striatum

The onset of abnormal movements in DYT1 dystonia is between childhood and adolescence, although it is unclear why clinical manifestations appear during this developmental period. Plasticity at corticostriatal synapses is critically involved in motor memory. In the Tor1a(+/Δgag) DYT1 dystonia mouse m...

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Udgivet i:eLife
Main Authors: Maltese, Marta, Stanic, Jennifer, Tassone, Annalisa, Sciamanna, Giuseppe, Ponterio, Giulia, Vanni, Valentina, Martella, Giuseppina, Imbriani, Paola, Bonsi, Paola, Mercuri, Nicola Biagio, Gardoni, Fabrizio, Pisani, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2018
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849413/
https://ncbi.nlm.nih.gov/pubmed/29504938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33331
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