Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine

DYT1 dystonia is a severe form of inherited dystonia, characterized by involuntary twisting movements and abnormal postures. It is linked to a deletion in the dyt1 gene, resulting in a mutated form of the protein torsinA. The penetrance for dystonia is incomplete, but both clinically affected and no...

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Detalhes bibliográficos
Main Authors: Martella, Giuseppina, Tassone, Annalisa, Sciamanna, Giuseppe, Platania, Paola, Cuomo, Dario, Viscomi, Maria Teresa, Bonsi, Paola, Cacci, Emanuele, Biagioni, Stefano, Usiello, Alessandro, Bernardi, Giorgio, Sharma, Nutan, Standaert, David G., Pisani, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766181/
https://ncbi.nlm.nih.gov/pubmed/19641103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awp194
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