Deficiency of liver-derived insulin-like growth factor-I (IGF-I) does not interfere with the skin wound healing rate

OBJECTIVE: IGF-I is a growth factor, which is expressed in virtually all tissues. The circulating IGF-I is however derived mainly from the liver. IGF-I promotes wound healing and its levels are decreased in wounds with low regenerative potential such as diabetic wounds. However, the contribution of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Botusan, Ileana Ruxandra, Zheng, Xiaowei, Narayanan, Sampath, Grünler, Jacob, Sunkari, Vivekananda Gupta, Calissendorff, Freja S., Ansurudeen, Ishrath, Illies, Christopher, Svensson, Johan, Jansson, John-Olov, Ohlsson, Claes, Brismar, Kerstin, Catrina, Sergiu-Bogdan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849293/
https://ncbi.nlm.nih.gov/pubmed/29534073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193084
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