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Liver-Derived IGF-I Regulates Mean Life Span in Mice
BACKGROUND: Transgenic mice with low levels of global insulin-like growth factor-I (IGF-I) throughout their life span, including pre- and postnatal development, have increased longevity. This study investigated whether specific deficiency of liver-derived, endocrine IGF-I is of importance for life s...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3143189/ https://ncbi.nlm.nih.gov/pubmed/21799924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022640 |
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